Effectiveness of Lemongrass Extract (Cymbopogon citratus) in Hand Sanitizer Formulation Against Bacteria

Effectiveness of Lemongrass Extract (Cymbopogon citratus) in Hand Sanitizer Formulation Against Bacteria

Authors

  • Risma Aprilia Department of Chemistry, Universitas Nusa Bangsa
  • Nurlela Nurlela SCOPUS ID: 57193951340 (Organic Chemistry) Department of Chemistry, Universitas Nusa Bangsa
  • Devy Susanty Department of Chemistry, Universitas Nusa Bangsa

DOI:

https://doi.org/10.31938/jsn.v13i4.480

Keywords:

Hand sanitizer, Lemongrass, Antibacterial, Stability

Abstract

Alcohol as an antiseptic ingredient in hand sanitizers is claimed to be less safe for health because alcohol causes dry skin and irritation to the skin with repeated use. Natural-based antiseptics are generally relatively safe. The plant that has the potential to be developed as an antiseptic is lemongrass (Cymbopogon citratus) because it contains citronellal, geraniol, and citronellol compounds. The aim of the study was to determine the effectiveness of lemongrass in the formulation of hand sanitizer gel through antibacterial and stability tests, including organoleptic, pH, and homogeneity. The results showed that a concentration of 10% w/v was the most active of using lemongrass extract in the hand sanitizer gel formulation. Based on the antibacterial test using the disc diffusion method, lemongrass extract (10%) had moderate activity against Staphylococcus aureus and Escherichia coli bacteria. Meanwhile, a hand sanitizer with 10% lemongrass extract has strong antibacterial activity against S. aureus and E. coli. The stability test results showed that the hand sanitizer has a turbid colour, characteristic lemongrass odour, semi-solid form, pH 6, and is homogeneous. However, the antibacterial activity of the hand sanitizer gel decreased with the length of storage time. Further research is needed to optimize the hand sanitizer formulation.

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Author Biography

Nurlela Nurlela, SCOPUS ID: 57193951340 (Organic Chemistry) Department of Chemistry, Universitas Nusa Bangsa

References

Anggreini, C. K., & Asngad, A. (2018). Hand sanitizer dalam bentuk gel dari daun serai dengan penambahan alkohol dan triklosan. Prosiding Seminar Nasional Pendidikan Biologi dan Saintek Ke-3 (hal. 126-130). Universitas Muhammadiyah Surakarta, Surakarta, Indonesia.

Aponno, J. V., Paulina V. Y. Y., & Hamidah, S. S. (2014). Uji efektivitas sediaan gel ekstrak etanol daun jambu biji (Psidium guajava Linn) terhadap penyembuhan luka yang terinfeksi bakteri Staphylococcus aureus pada kelinci (Orytolagus cuniculus). Pharmacon Jurnal Ilmiah Farmasi, 3(3), 279-286.

Emrizal & Zuraida, S. (2018). Uji aktivitas antibakteri ekstrak etanol buah kemukus (Piper cubeba L. F) terhadap bakteri Escherichia coli dan Staphylococcus aureus. Jurnal Penelitian Farmasi Indonesia, 6(2), 72-75.

Fatimah, C., & Ardiani, R. (2018). Pembuatan hand sanitizer (pembersih tangan tanpa air) menggunakan antiseptik bahan alami. Prosiding Seminar Nasional Hasil Pengabdian, 1(1). Universitas Muslim Nusantara Al-Washliyah Medan, Sumatera Utara, Indonesia.

Jalaluddin, Amri, A., & Sari, N. (2018). Pemanfaatan minyak sereh (Cymbopogon nardus L) sebagai antioksidan pada sabun mandi padat. Jurnal Teknologi Kimia Unimal, 7(1), 52-60.

Manus, N., Yamlean, P. V. Y., & Kojong, N. S. (2016). Formulasi sediaan gel minyak atsiri daun sereh (Cymbopogon citratus) sebagai antiseptik tangan. Pharmacon Jurnal Ilmiah Farmasi, 5(3), 85-93.

Pertiwi, G. P., Ifttitah, E. D., & Suratmo, S. (2014). Pengaruh lama waktu penyimpanan dan penyinaran cahaya terhadap sitronelal serta uji toksisitas dengan menggunakan metode BSLT (Brine Shrimp Lethality Test). Jurnal Ilmu Kimia Universitas Brawijaya, 1(1), 98-104.

Putri, V. A. D., Posangi, J., Nangoy, E., & Bara, R. A. (2016). Uji daya hambat jamur endofit rimpang lengkuas (Alpinia galanga L.) terhadap pertumbuhan bakteri Escherichia coli dan Staphylococcus aureus. Jurnal e-Biomedik (eBm), 4(2), 1-8.

Rahman, H. (2013). Bioaktivitas minyak atsiri sereh Cymbopogon citratus DC. terhadap pertumbuhan bakteri Eschericia coli dan Staphylococcus aureus (skripsi). Universitas Hasanuddin, Makassar, Sulawesi, Indonesia.

Rahmi, A., Hardi, N., Hevira, L., & Bukittinggi, M. N. (2021). Aktivitas antioksidan ekstrak kulit pisang kepok, pisang mas dan pisang nangka menggunakan metode DPPH. Jurnal Ilmu Farmasi & Farmasi Klinik, 18(2), 77–84.

Santoso, J., Herowati, R., & Murrukhmihadi, M. (2018). Optimasi formula krim ekstrak poliherbal sebagai antibakteri dengan kombinasi gliserin, sorbitol dan propilenglikol sebagai humektan. Jurnal Para Pemikir, 7(2), 270-274.

Sarlina, S., Razak, A. R., & Tandah, M. R. (2017). Uji aktivitas antibakteri sediaan gel ekstrak daun sereh (Cymbopogon nardus L. Rendle) terhadap bakteri Staphylococcus aureus penyebab jerawat. Jurnal Farmasi Galenika, 3(2), 143-149. doi:10.22487/j24428744.2017.v3.i2.8770

Sayuti, N. A. (2015). Formulasi dan uji stabilitas fisik sediaan gel ekstrak daun ketepeng cina (Cassia alata L.). Jurnal Kefarmasian Indonesia, 5(2), 74-82.

Simatupang, E J. 2018. Formulasi sediaan gel hand sanitizer dari ekstrak etanol daun jambu air (Syzygium aqueum Burm. F) Alston) (skripsi). Institut Kesehatan Halvatea, Medan, Sumatera, Indonesia.

Sharma, D., Patel, R. P., Zaidi, S. T. R., Sarker, M. M. R., Lean, Q. Y., & Ming, L. C. (2017). Interplay of the quality of ciprofloxacin and antibiotic resistance in developing countries. Frontiers in Pharmacology, 8. doi:10.3389/fphar.2017.00546

Utami, Y. P., Abdul, H. U., Reny, S., & Indah, K. (2017). Standardisasi simplisia dan ekstrak etanol daun leilem (Clerodendrum minahassae Teisjm. & Binn.). Journal of Pharmaceutical and Medicinal Sciences, 2(1), 32-39.

Wangkanusa, D., Lolo, W. A., & Wewengkang, D. S. (2016). Uji aktivitas antibakteri dari ekstrak daun prasman (Eupatorium triplinerve Vahl.) terhadap pertumbuhan bakteri Staphylococcus aureus dan Pseudomonas aeruginosa. Pharmacon Jurnal Ilmiah Farmasi, 5(4), 203-210.

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Published

2023-11-12

How to Cite

Aprilia, R., Nurlela, N., & Susanty, D. (2023). Effectiveness of Lemongrass Extract (Cymbopogon citratus) in Hand Sanitizer Formulation Against Bacteria. JURNAL SAINS NATURAL, 13(4), 176–182. https://doi.org/10.31938/jsn.v13i4.480

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